Globular Adiponectin Limits Microglia Pro-Inflammatory Phenotype through an AdipoR1/NF-κB Signaling Pathway

We recently reported that increased levels of Adiponectin (ApN) in the brain led to microglia phenotype and activation state regulation, thus reducing both global brain inflammation and depressive-like behaviors in mice. Apart from this, little is known on ApN molecular effects on microglia, althoug...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Nicolas, Sarah, Cazareth, Julie, Zarif, Hadi, Guyon, Alice, Heurteaux, Catherine, Chabry, Joëlle, Petit-Paitel, Agnès
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5694456/
https://ncbi.nlm.nih.gov/pubmed/29184485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2017.00352
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