Heterotrimeric G‐protein subunit Gα (i2) contributes to agonist‐sensitive apoptosis and degranulation in murine platelets

Gα (i2), a heterotrimeric G‐protein subunit, regulates various cell functions including ion channel activity, cell differentiation, proliferation and apoptosis. Platelet‐expressed Gα (i2) is decisive for the extent of tissue injury following ischemia/reperfusion. However, it is not known whether Gα...

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Veröffentlicht in:Physiol Rep
Hauptverfasser: Cao, Hang, Qadri, Syed M., Lang, Elisabeth, Pelzl, Lisann, Umbach, Anja T., Leiss, Veronika, Birnbaumer, Lutz, Nürnberg, Bernd, Pieske, Burkert, Voelkl, Jakob, Gawaz, Meinrad, Bissinger, Rosi, Lang, Florian
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125243/
https://ncbi.nlm.nih.gov/pubmed/30187671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13841
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