Chikungunya virus impairs draining lymph node function by inhibiting HEV-mediated lymphocyte recruitment

Chikungunya virus (CHIKV) causes acute and chronic rheumatologic disease. Pathogenic CHIKV strains persist in joints of immunocompetent mice, while the attenuated CHIKV strain 181/25 is cleared by adaptive immunity. We analyzed the draining lymph node (dLN) to define events in lymphoid tissue that m...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:JCI Insight
Prif Awduron: McCarthy, Mary K., Davenport, Bennett J., Reynoso, Glennys V., Lucas, Erin D., May, Nicholas A., Elmore, Susan A., Tamburini, Beth A., Hickman, Heather D., Morrison, Thomas E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2018
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124534/
https://ncbi.nlm.nih.gov/pubmed/29997290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.121100
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg