Chikungunya virus impairs draining lymph node function by inhibiting HEV-mediated lymphocyte recruitment

Chikungunya virus (CHIKV) causes acute and chronic rheumatologic disease. Pathogenic CHIKV strains persist in joints of immunocompetent mice, while the attenuated CHIKV strain 181/25 is cleared by adaptive immunity. We analyzed the draining lymph node (dLN) to define events in lymphoid tissue that m...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:JCI Insight
Hlavní autoři: McCarthy, Mary K., Davenport, Bennett J., Reynoso, Glennys V., Lucas, Erin D., May, Nicholas A., Elmore, Susan A., Tamburini, Beth A., Hickman, Heather D., Morrison, Thomas E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124534/
https://ncbi.nlm.nih.gov/pubmed/29997290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.121100
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky