A porcine model of neurofibromatosis type 1 that mimics the human disease

Loss of the NF1 tumor suppressor gene causes the autosomal dominant condition, neurofibromatosis type 1 (NF1). Children and adults with NF1 suffer from pathologies including benign and malignant tumors to cognitive deficits, seizures, growth abnormalities, and peripheral neuropathies. NF1 encodes ne...

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Bibliografische gegevens
Gepubliceerd in:JCI Insight
Hoofdauteurs: White, Katherine A., Swier, Vicki J., Cain, Jacob T., Kohlmeyer, Jordan L., Meyerholz, David K., Tanas, Munir R., Uthoff, Johanna, Hammond, Emily, Li, Hua, Rohret, Frank A., Goeken, Adam, Chan, Chun-Hung, Leidinger, Mariah R., Umesalma, Shaikamjad, Wallace, Margaret R., Dodd, Rebecca D., Panzer, Karin, Tang, Amy H., Darbro, Benjamin W., Moutal, Aubin, Cai, Song, Li, Wennan, Bellampalli, Shreya S., Khanna, Rajesh, Rogers, Christopher S., Sieren, Jessica C., Quelle, Dawn E., Weimer, Jill M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2018
Onderwerpen:
Technical Advance
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124439/
https://ncbi.nlm.nih.gov/pubmed/29925695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.120402
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