Aldosterone deficiency in mice burdens respiration and accentuates diet-induced hyperinsulinemia and obesity

Aldosterone synthase inhibitors (ASIs) should alleviate obesity-related cardiovascular and renal problems resulting partly from aldosterone excess, but their clinical use may have limitations. To improve knowledge for the use of ASIs, we investigated physiology in aldosterone synthase–knockout (ASKO...

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Vydáno v:JCI Insight
Hlavní autoři: Liao, Wan-Hui, Suendermann, Claudia, Steuer, Andrea Eva, Pacheco Lopez, Gustavo, Odermatt, Alex, Faresse, Nourdine, Henneberg, Maciej, Langhans, Wolfgang
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2018
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124420/
https://ncbi.nlm.nih.gov/pubmed/30046010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99015
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