Aldosterone deficiency in mice burdens respiration and accentuates diet-induced hyperinsulinemia and obesity

Aldosterone synthase inhibitors (ASIs) should alleviate obesity-related cardiovascular and renal problems resulting partly from aldosterone excess, but their clinical use may have limitations. To improve knowledge for the use of ASIs, we investigated physiology in aldosterone synthase–knockout (ASKO...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Liao, Wan-Hui, Suendermann, Claudia, Steuer, Andrea Eva, Pacheco Lopez, Gustavo, Odermatt, Alex, Faresse, Nourdine, Henneberg, Maciej, Langhans, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124420/
https://ncbi.nlm.nih.gov/pubmed/30046010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99015
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