Intracapillary immune complexes recruit and activate slan-expressing CD16(+) monocytes in human lupus nephritis

Lupus nephritis is a major cause of morbidity in patients with systemic lupus erythematosus. Among the different types of lupus nephritis, intracapillary immune complex (IC) deposition and accumulation of monocytes are hallmarks of lupus nephritis class III and IV. The relevance of intracapillary IC...

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Udgivet i:JCI Insight
Main Authors: Olaru, Florina, Döbel, Thomas, Lonsdorf, Anke S., Oehrl, Stephanie, Maas, Michael, Enk, Alexander H., Schmitz, Marc, Gröne, Elisabeth F., Gröne, Hermann-J., Schäkel, Knut
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124405/
https://ncbi.nlm.nih.gov/pubmed/29875315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.96492
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