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Lens-specific deletion of the Msx2 gene increased apoptosis by enhancing the caspase-3/caspase-8 signaling pathway
OBJECTIVE: To investigate the influence of Msx2 conditional gene knockout during lens development in mice. METHODS: Lens-specific Msx2 knockout mice were generated using the Cre-loxP system. The eyes of Msx2 conditional knockout (Msx2CKO) and wild-type (Msx2WT) mice were examined during embryonic an...
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| Publicado no: | J Int Med Res |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6124292/ https://ncbi.nlm.nih.gov/pubmed/29921154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0300060518774687 |
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