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c-Maf increases apoptosis in peripheral CD8 cells by transactivating Caspase 6
In addition to transactivation of interleukin-4 (IL-4), cellular muscular aponeurotic fibrosarcoma (c-Maf) enhances CD4 cell apoptosis by limiting Bcl-2 expression. The CD8 cells also express c-Maf and peripheral CD8 cell numbers are reduced in c-Maf transgenic mice, suggesting that c-Maf may influe...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Science Inc
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2691792/ https://ncbi.nlm.nih.gov/pubmed/19476513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.03014.x |
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