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c-Maf increases apoptosis in peripheral CD8 cells by transactivating Caspase 6

In addition to transactivation of interleukin-4 (IL-4), cellular muscular aponeurotic fibrosarcoma (c-Maf) enhances CD4 cell apoptosis by limiting Bcl-2 expression. The CD8 cells also express c-Maf and peripheral CD8 cell numbers are reduced in c-Maf transgenic mice, suggesting that c-Maf may influe...

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Detalhes bibliográficos
Main Authors: Peng, Siying, Wu, Hailong, Mo, Yin-Yuan, Watabe, Kounosuke, Pauza, Mary E
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691792/
https://ncbi.nlm.nih.gov/pubmed/19476513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.03014.x
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