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Integrin α5β1-Ang1/Tie2 receptor cross-talk regulates brain endothelial cell responses following cerebral ischemia

We have previously demonstrated that in response to cerebral ischemia (CI), the growth factor angiopoietin-1 (Ang1) and α5β1 integrin are both induced in cerebral vessels, which likely provide positive signals driving the endogenous angiogenic response and vascular protection after CI. However, the...

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Détails bibliographiques
Publié dans:Exp Mol Med
Auteurs principaux: Pang, Defang, Wang, Lu, Dong, Jing, Lai, Xiaoyin, Huang, Qijuan, Milner, Richard, Li, Longxuan
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6123805/
https://ncbi.nlm.nih.gov/pubmed/30185785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-018-0145-7
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