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Stable interaction between α5β1 integrin and Tie2 tyrosine kinase receptor regulates endothelial cell response to Ang-1

During angiogenic remodeling, Ang-1, the ligand of Tie2 tyrosine kinase, is involved in vessel sprouting and stabilization through unclear effects on nascent capillaries and mural cells. In our study, we hypothesized that the Ang-1/Tie2 system could cross-talk with integrins, and be influenced by th...

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Detalhes bibliográficos
Main Authors: Cascone, Ilaria, Napione, Lucia, Maniero, Fabrizio, Serini, Guido, Bussolino, Federico
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171441/
https://ncbi.nlm.nih.gov/pubmed/16157706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200507082
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