Expression map of 78 brain-expressed mouse orphan GPCRs provides a translational resource for neuropsychiatric research

Orphan G-protein-coupled receptors (oGPCRs) possess untapped potential for drug discovery. In the brain, oGPCRs are generally expressed at low abundance and their function is understudied. Expression profiling is an essential step to position oGPCRs in brain function and disease, however public data...

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Publicat a:Commun Biol
Autors principals: Ehrlich, Aliza T., Maroteaux, Grégoire, Robe, Anne, Venteo, Lydie, Nasseef, Md. Taufiq, van Kempen, Leon C., Mechawar, Naguib, Turecki, Gustavo, Darcq, Emmanuel, Kieffer, Brigitte L.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6123746/
https://ncbi.nlm.nih.gov/pubmed/30271982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-018-0106-7
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