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BK channel deacetylation by SIRT1 in dentate gyrus regulates anxiety and response to stress
Previous genomic studies in humans indicate that SIRT1, a nicotinamide adenine dinucleotide (NAD+)-dependent protein deacetylase, is involved in anxiety and depression, but the mechanisms are unclear. We previously showed that SIRT1 is highly activated in the nuclear fraction of the dentate gyrus of...
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| 發表在: | Commun Biol |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6123630/ https://ncbi.nlm.nih.gov/pubmed/30271963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-018-0088-5 |
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