Tyrosine kinase receptor TIE-1 mediates platinum resistance by promoting nucleotide excision repair in ovarian cancer

Platinum resistance is one of the most challenging problems in ovarian cancer treatment. High-throughput functional siRNA screening identified tyrosine kinase with immunoglobulin-like and EGF-like domains 1 (TIE-1) as a gene that confers cells resistant to cisplatin. Conversely enforced over-express...

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Foilsithe in:Sci Rep
Main Authors: Ishibashi, Masumi, Toyoshima, Masafumi, Zhang, Xuewei, Hasegawa-Minato, Junko, Shigeta, Shogo, Usui, Toshinori, Kemp, Christopher J., Grandori, Carla, Kitatani, Kazuyuki, Yaegashi, Nobuo
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2018
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6123490/
https://ncbi.nlm.nih.gov/pubmed/30181600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31069-2
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