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TXNDC5 synergizes with HSC70 to exacerbate the inflammatory phenotype of synovial fibroblasts in rheumatoid arthritis through NF-κB signaling

The upregulated expression of thioredoxin domain-containing protein 5 (TXNDC5) is associated with rheumatoid arthritis in patients and model mice. However, the underlying mechanism by which TXNDC5 influences the pathological activation of rheumatoid arthritis synovial fibroblasts (RASFs) remains unk...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Mol Immunol
Egile Nagusiak: Wang, Lin, Dong, Hongyan, Song, Guanhua, Zhang, Rui, Pan, Jihong, Han, Jinxiang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6123406/
https://ncbi.nlm.nih.gov/pubmed/28603283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2017.20
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