TXNDC5 synergizes with HSC70 to exacerbate the inflammatory phenotype of synovial fibroblasts in rheumatoid arthritis through NF-κB signaling

The upregulated expression of thioredoxin domain-containing protein 5 (TXNDC5) is associated with rheumatoid arthritis in patients and model mice. However, the underlying mechanism by which TXNDC5 influences the pathological activation of rheumatoid arthritis synovial fibroblasts (RASFs) remains unk...

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Vydáno v:Cell Mol Immunol
Hlavní autoři: Wang, Lin, Dong, Hongyan, Song, Guanhua, Zhang, Rui, Pan, Jihong, Han, Jinxiang
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6123406/
https://ncbi.nlm.nih.gov/pubmed/28603283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2017.20
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