Phosphorylation of the Amyloid-Beta Peptide Inhibits Zinc-Dependent Aggregation, Prevents Na,K-ATPase Inhibition, and Reduces Cerebral Plaque Deposition

The triggers of late-onset sporadic Alzheimer’s disease (AD) are still poorly understood. Impairment of protein phosphorylation with age is well-known; however, the role of the phosphorylation in β-amyloid peptide (Aβ) is not studied sufficiently. Zinc-induced oligomerization of Aβ represents a pote...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Barykin, Evgeny P., Petrushanko, Irina Y., Kozin, Sergey A., Telegin, Georgy B., Chernov, Alexander S., Lopina, Olga D., Radko, Sergey P., Mitkevich, Vladimir A., Makarov, Alexander A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6123382/
https://ncbi.nlm.nih.gov/pubmed/30210292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00302
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados