Pioglitazone, a PPAR-γ Activator, Stimulates BK(Ca) but Suppresses IK(M) in Hippocampal Neurons

Pioglitazone (PIO), a thiazolidinedone, was reported to stimulate peroxisome proliferator-activated receptor-γ (PPAR-γ) with anti-inflammatory, anti-proliferative, anti-diabetic, and antidepressive activities. However, whether this compound exerts any perturbations on Ca(2+)-activated K(+) and M-typ...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Front Pharmacol
मुख्य लेखकों: Chen, Tsang-Shan, Lai, Ming-Chi, Hung, Te-Yu, Lin, Kao-Min, Huang, Chin-Wei, Wu, Sheng-Nan
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Frontiers Media S.A. 2018
विषय:
Pharmacology
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6123368/
https://ncbi.nlm.nih.gov/pubmed/30210346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00977
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