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Donor Pre-treatment with nebulized complement C3a Receptor antagonist mitigates brain-death induced immunological injury post-lung transplant

Donor brain death (BD) is an inherent part of lung transplantation (LTx) and a key contributor to ischemia-reperfusion injury (IRI). Complement activation occurs as a consequence of BD in other solid organ Tx and exacerbates IRI, but the role of complement in LTx has not been investigated. Here, we...

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Detalhes bibliográficos
Publicado no:Am J Transplant
Main Authors: Cheng, Qi, Patel, Kunal, Lei, Biao, Rucker, Lindsay, Allen, D. Patterson, Zhu, Peng, Vasu, Chentha, Martins, Paulo N., Goddard, Martin, Nadig, Satish N., Atkinson, Carl
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6123303/
https://ncbi.nlm.nih.gov/pubmed/29504277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.14717
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