Donor Brain Death Exacerbates Complement-Dependent Ischemia Reperfusion Injury in Transplanted Hearts

BACKGROUND: Brain death (BD) can immunologically prime the donor organ and is thought to lead to exacerbated ischemia reperfusion injury (IRI) post-transplantation. Using a newly developed mouse model of BD, we investigated the effect of donor BD on post transplant cardiac IRI. We further investigat...

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Hauptverfasser: Atkinson, Carl, Floerchinger, Bernhard, Qiao, Fei, Casey, Sarah, Williamson, Tucker, Moseley, Ellen, Stoica, Serban, Goddard, Martin, Ge, Xupeng, Tullius, Stefan G., Tomlinson, Stephen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721358/
https://ncbi.nlm.nih.gov/pubmed/23443736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.112.000784
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