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Shedding of CD16 disassembles the NK cell immune synapse and boosts serial engagement of target cells
Natural Killer (NK) cells can engage multiple virally infected or tumor cells sequentially and deliver perforin for cytolytic killing of these targets. Using microscopy to visualize degranulation from individual NK cells, we found that repeated activation via the Fc receptor CD16 decreased the amoun...
Gorde:
| Argitaratua izan da: | J Cell Biol |
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| Egile Nagusiak: | , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Rockefeller University Press
2018
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6122987/ https://ncbi.nlm.nih.gov/pubmed/29967280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201712085 |
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