BCAP links IL-1R to the PI3K–mTOR pathway and regulates pathogenic Th17 cell differentiation

The toll-like receptor (TLR) and interleukin (IL)–1 family of receptors share several signaling components, including the most upstream adapter, MyD88. We previously reported the discovery of B cell adapter for phosphoinositide 3-kinase (BCAP) as a novel toll–IL-1 receptor homology domain–containing...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Deason, Krystin, Troutman, Ty Dale, Jain, Aakanksha, Challa, Dilip K., Mandraju, Rajakumar, Brewer, Travis, Ward, E. Sally, Pasare, Chandrashekhar
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122979/
https://ncbi.nlm.nih.gov/pubmed/30093533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171810
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