TLR signaling adapter BCAP regulates inflammatory to reparatory macrophage transition by promoting histone lactylation

Macrophages respond to microbial ligands and various noxious cues by initiating an inflammatory response aimed at eliminating the original pathogenic insult. Transition of macrophages from a proinflammatory state to a reparative state, however, is vital for resolution of inflammation and return to h...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Irizarry-Caro, Ricardo A., McDaniel, Margaret M., Overcast, Garrett R., Jain, Viral G., Troutman, Ty Dale, Pasare, Chandrashekhar
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720107/
https://ncbi.nlm.nih.gov/pubmed/33199625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2009778117
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