TLR signaling adapter BCAP regulates inflammatory to reparatory macrophage transition by promoting histone lactylation

Macrophages respond to microbial ligands and various noxious cues by initiating an inflammatory response aimed at eliminating the original pathogenic insult. Transition of macrophages from a proinflammatory state to a reparative state, however, is vital for resolution of inflammation and return to h...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Irizarry-Caro, Ricardo A., McDaniel, Margaret M., Overcast, Garrett R., Jain, Viral G., Troutman, Ty Dale, Pasare, Chandrashekhar
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720107/
https://ncbi.nlm.nih.gov/pubmed/33199625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2009778117
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