Anticancer activity of paclitaxel-loaded keratin nanoparticles in two-dimensional and perfused three-dimensional breast cancer models

PURPOSE: Taxanes are highly effective cytotoxic drugs for progressing breast cancer treatment. However, their poor solubility and high toxicity urge the development of innovative formulations of potential clinical relevance. MATERIALS AND METHODS: By using a simple and straightforward aggregation me...

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Vydáno v:Int J Nanomedicine
Hlavní autoři: Foglietta, Federica, Spagnoli, Giulio C, Muraro, Manuele Giuseppe, Ballestri, Marco, Guerrini, Andrea, Ferroni, Claudia, Aluigi, Annalisa, Sotgiu, Giovanna, Varchi, Greta
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2018
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122896/
https://ncbi.nlm.nih.gov/pubmed/30214193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S159942
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