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Anticancer activity of paclitaxel-loaded keratin nanoparticles in two-dimensional and perfused three-dimensional breast cancer models

PURPOSE: Taxanes are highly effective cytotoxic drugs for progressing breast cancer treatment. However, their poor solubility and high toxicity urge the development of innovative formulations of potential clinical relevance. MATERIALS AND METHODS: By using a simple and straightforward aggregation me...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Foglietta, Federica, Spagnoli, Giulio C, Muraro, Manuele Giuseppe, Ballestri, Marco, Guerrini, Andrea, Ferroni, Claudia, Aluigi, Annalisa, Sotgiu, Giovanna, Varchi, Greta
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122896/
https://ncbi.nlm.nih.gov/pubmed/30214193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S159942
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