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Anticancer activity of paclitaxel-loaded keratin nanoparticles in two-dimensional and perfused three-dimensional breast cancer models

PURPOSE: Taxanes are highly effective cytotoxic drugs for progressing breast cancer treatment. However, their poor solubility and high toxicity urge the development of innovative formulations of potential clinical relevance. MATERIALS AND METHODS: By using a simple and straightforward aggregation me...

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Publicat a:Int J Nanomedicine
Autors principals: Foglietta, Federica, Spagnoli, Giulio C, Muraro, Manuele Giuseppe, Ballestri, Marco, Guerrini, Andrea, Ferroni, Claudia, Aluigi, Annalisa, Sotgiu, Giovanna, Varchi, Greta
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122896/
https://ncbi.nlm.nih.gov/pubmed/30214193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S159942
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