Anticancer activity of paclitaxel-loaded keratin nanoparticles in two-dimensional and perfused three-dimensional breast cancer models

PURPOSE: Taxanes are highly effective cytotoxic drugs for progressing breast cancer treatment. However, their poor solubility and high toxicity urge the development of innovative formulations of potential clinical relevance. MATERIALS AND METHODS: By using a simple and straightforward aggregation me...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Nanomedicine
Prif Awduron: Foglietta, Federica, Spagnoli, Giulio C, Muraro, Manuele Giuseppe, Ballestri, Marco, Guerrini, Andrea, Ferroni, Claudia, Aluigi, Annalisa, Sotgiu, Giovanna, Varchi, Greta
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Dove Medical Press 2018
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122896/
https://ncbi.nlm.nih.gov/pubmed/30214193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S159942
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