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Population pharmacokinetics of mefloquine given as a 3-day artesunate–mefloquine in patients with acute uncomplicated Plasmodium falciparum malaria in a multidrug-resistant area along the Thai–Myanmar border

BACKGROUND: Low mefloquine exposure has been shown to contribute to treatment failure in patients with uncomplicated falciparum malaria following a 3-day artesunate–mefloquine combination. The present study aimed to develop a population pharmacokinetic model for mefloquine based on whole blood conce...

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Detalhes bibliográficos
Publicado no:Malar J
Main Authors: Hoglund, Richard M., Ruengweerayut, Ronnatrai, Na-Bangchang, Kesara
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122721/
https://ncbi.nlm.nih.gov/pubmed/30176888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-018-2466-3
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