Identification of resistance of Plasmodium falciparum to artesunate-mefloquine combination in an area along the Thai-Myanmar border: integration of clinico-parasitological response, systemic drug exposure, and in vitro parasite sensitivity

BACKGROUND: A markedly high failure rate of three-day artesunate-mefloquine was observed in the area along the Thai-Myanmar border. METHODS: Identification of Plasmodium falciparum isolates with intrinsic resistance to each component of the artesunate-mefloquine combination was analysed with integra...

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Detalhes bibliográficos
Main Authors: Na-Bangchang, Kesara, Muhamad, Phunuch, Ruaengweerayut, Ronnatrai, Chaijaroenkul, Wanna, Karbwang, Juntra
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737112/
https://ncbi.nlm.nih.gov/pubmed/23898808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-12-263
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