Alleviation of endoplasmic reticulum stress protects against cisplatin-induced ovarian damage

BACKGROUND: Cisplatin (CDDP), a widely used chemotherapeutic agent, can induce excessive granulosa cell apoptosis, follicle loss and even premature ovarian insufficiency (POI). However, the mechanism remains elusive, although some studies have indicated the involvement of endoplasmic reticulum stres...

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Detalhes bibliográficos
Publicado no:Reprod Biol Endocrinol
Main Authors: Wu, Yuping, Ma, Congshun, Zhao, Huihui, Zhou, Yuxia, Chen, Zhenguo, Wang, Liping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122480/
https://ncbi.nlm.nih.gov/pubmed/30176887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12958-018-0404-4
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