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Online structure-based screening of purchasable approved drugs and natural compounds: retrospective examples of drug repositioning on cancer targets

Drug discovery is a long and difficult process that benefits from the integration of virtual screening methods in experimental screening campaigns such as to generate testable hypotheses, accelerate and/or reduce the cost of drug development. Current drug attrition rate is still a major issue in all...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Lagarde, Nathalie, Rey, Julien, Gyulkhandanyan, Aram, Tufféry, Pierre, Miteva, Maria A., Villoutreix, Bruno O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122352/
https://ncbi.nlm.nih.gov/pubmed/30190791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25966
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