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Online structure-based screening of purchasable approved drugs and natural compounds: retrospective examples of drug repositioning on cancer targets

Drug discovery is a long and difficult process that benefits from the integration of virtual screening methods in experimental screening campaigns such as to generate testable hypotheses, accelerate and/or reduce the cost of drug development. Current drug attrition rate is still a major issue in all...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Lagarde, Nathalie, Rey, Julien, Gyulkhandanyan, Aram, Tufféry, Pierre, Miteva, Maria A., Villoutreix, Bruno O.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122352/
https://ncbi.nlm.nih.gov/pubmed/30190791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25966
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