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Pirfenidone suppresses bleomycin-induced pulmonary fibrosis and periostin expression in rats

The aim of the present study was to investigate the effect of pirfenidone on bleomycin-induced lung fibrosis in rats, in order to elucidate the underlying mechanism of periostin-induced fibrosis. The lung fibrosis model was constructed using a single intratracheal instillation of bleomycin in rats....

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Pubblicato in:Exp Ther Med
Autori principali: Song, Xiaoxia, Yu, Wencheng, Guo, Fang
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122328/
https://ncbi.nlm.nih.gov/pubmed/30186404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2018.6378
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