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Thiaminase I Provides a Growth Advantage by Salvaging Precursors from Environmental Thiamine and Its Analogs in Burkholderia thailandensis

Thiamine is essential to life, as it serves as a cofactor for enzymes involved in critical carbon transformations. Many bacteria can synthesize thiamine, while thiamine auxotrophs must obtain it or its precursors from the environment. Thiaminases degrade thiamine by catalyzing the base-exchange subs...

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Bibliographische Detailangaben
Veröffentlicht in:Appl Environ Microbiol
Hauptverfasser: Sannino, David R., Kraft, Clifford E., Edwards, Katie A., Angert, Esther R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122001/
https://ncbi.nlm.nih.gov/pubmed/30006396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01268-18
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