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Thiaminase I Provides a Growth Advantage by Salvaging Precursors from Environmental Thiamine and Its Analogs in Burkholderia thailandensis

Thiamine is essential to life, as it serves as a cofactor for enzymes involved in critical carbon transformations. Many bacteria can synthesize thiamine, while thiamine auxotrophs must obtain it or its precursors from the environment. Thiaminases degrade thiamine by catalyzing the base-exchange subs...

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Publicado en:Appl Environ Microbiol
Main Authors: Sannino, David R., Kraft, Clifford E., Edwards, Katie A., Angert, Esther R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122001/
https://ncbi.nlm.nih.gov/pubmed/30006396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01268-18
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