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Diversity and Proliferation of Metallo-β-Lactamases: a Clarion Call for Clinically Effective Metallo-β-Lactamase Inhibitors

The worldwide proliferation of life-threatening metallo-β-lactamase (MBL)-producing Gram-negative bacteria is a serious concern to public health. MBLs are compromising the therapeutic efficacies of β-lactams, particularly carbapenems, which are last-resort antibiotics indicated for various multidrug...

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Publicado en:Appl Environ Microbiol
Autores principales: Somboro, Anou M., Osei Sekyere, John, Amoako, Daniel G., Essack, Sabiha Y., Bester, Linda A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6121990/
https://ncbi.nlm.nih.gov/pubmed/30006399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00698-18
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