Cryo-EM of the dynamin polymer assembled on lipid membrane

Membrane fission is a fundamental process in the regulation and remodeling of cell membranes. Dynamin, a large GTPase, mediates membrane fission by assembling around, constricting and cleaving the necks of budding vesicles(1). Here, we report a 3.75 Å resolution cryo-EM structure of the membrane-ass...

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Gepubliceerd in:Nature
Hoofdauteurs: Kong, Leopold, Sochacki, Kem A., Wang, Huaibin, Fang, Shunming, Canagarajah, Bertram, Kehr, Andrew D., Rice, William J., Strub, Marie-Paule, Taraska, Justin W., Hinshaw, Jenny E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6121775/
https://ncbi.nlm.nih.gov/pubmed/30069048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0378-6
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