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Using Persistent Homology as a New Approach for Super-Resolution Localization Microscopy Data Analysis and Classification of γH2AX Foci/Clusters

DNA double strand breaks (DSB) are the most severe damages in chromatin induced by ionizing radiation. In response to such environmentally determined stress situations, cells have developed repair mechanisms. Although many investigations have contributed to a detailed understanding of repair process...

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Pubblicato in:Int J Mol Sci
Autori principali: Hofmann, Andreas, Krufczik, Matthias, Heermann, Dieter W., Hausmann, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6121565/
https://ncbi.nlm.nih.gov/pubmed/30072594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19082263
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