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Using Persistent Homology as a New Approach for Super-Resolution Localization Microscopy Data Analysis and Classification of γH2AX Foci/Clusters

DNA double strand breaks (DSB) are the most severe damages in chromatin induced by ionizing radiation. In response to such environmentally determined stress situations, cells have developed repair mechanisms. Although many investigations have contributed to a detailed understanding of repair process...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Hofmann, Andreas, Krufczik, Matthias, Heermann, Dieter W., Hausmann, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6121565/
https://ncbi.nlm.nih.gov/pubmed/30072594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19082263
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