Ulk2 controls cortical excitatory–inhibitory balance via autophagic regulation of p62 and GABA(A) receptor trafficking in pyramidal neurons

Autophagy plays an essential role in intracellular degradation and maintenance of cellular homeostasis in all cells, including neurons. Although a recent study reported a copy number variation of Ulk2, a gene essential for initiating autophagy, associated with a case of schizophrenia (SZ), it remain...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Sumitomo, Akiko, Yukitake, Hiroshi, Hirai, Kazuko, Horike, Kouta, Ueta, Keisho, Chung, Youjin, Warabi, Eiji, Yanagawa, Toru, Kitaoka, Shiho, Furuyashiki, Tomoyuki, Narumiya, Shuh, Hirano, Tomoo, Niwa, Minae, Sibille, Etienne, Hikida, Takatoshi, Sakurai, Takeshi, Ishizuka, Koko, Sawa, Akira, Tomoda, Toshifumi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6121199/
https://ncbi.nlm.nih.gov/pubmed/29893844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy219
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