A platform for phenotypic discovery of therapeutic antibodies and targets applied on Chronic Lymphocytic Leukemia

Development of antibody drugs against novel targets and pathways offers great opportunities to improve current cancer treatment. We here describe a phenotypic discovery platform enabling efficient identification of therapeutic antibody-target combinations. The platform utilizes primary patient cells...

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Veröffentlicht in:NPJ Precis Oncol
Hauptverfasser: Ljungars, A., Mårtensson, L., Mattsson, J., Kovacek, M., Sundberg, A., Tornberg, U-C., Jansson, B., Persson, N., Emruli, V. Kuci, Ek, S., Jerkeman, M., Hansson, M., Juliusson, G., Ohlin, M., Frendéus, B., Teige, I., Mattsson, M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Brief Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120912/
https://ncbi.nlm.nih.gov/pubmed/30182064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-018-0061-2
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