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Y1 receptor deficiency in β-cells leads to increased adiposity and impaired glucose metabolism

Insulin secretion from pancreatic β-cells is critical for maintaining glucose homeostasis and deregulation of circulating insulin levels is associated with the development of metabolic diseases. While many factors have been implicated in the stimulation of insulin secretion, the mechanisms that subs...

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Опубликовано в: :Sci Rep
Главные авторы: Loh, Kim, Shi, Yan-Chuan, Bensellam, Mohammed, Lee, Kailun, Laybutt, D. Ross, Herzog, Herbert
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120893/
https://ncbi.nlm.nih.gov/pubmed/30177746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30140-2
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