Promoter Usage and Dynamics in Vascular Smooth Muscle Cells Exposed to Fibroblast Growth Factor-2 or Interleukin-1β

Smooth muscle cells (SMC) in blood vessels are normally growth quiescent and transcriptionally inactive. Our objective was to understand promoter usage and dynamics in SMC acutely exposed to a prototypic growth factor or pro-inflammatory cytokine. Using cap analysis gene expression (FANTOM5 project)...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Alhendi, Ahmad M. N., Patrikakis, Margaret, Daub, Carsten O., Kawaji, Hideya, Itoh, Masayoshi, de Hoon, Michiel, Carninci, Piero, Hayashizaki, Yoshihide, Arner, Erik, Khachigian, Levon M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120868/
https://ncbi.nlm.nih.gov/pubmed/30177712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30702-4
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