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Suppression of IGF1R in Melanoma Cells by an Adenovirus-Mediated One-Step Knockdown System

Abnormal activation of the IGF1R signaling pathway accelerates melanoma development and metastases. RNAi systems with complex cloning procedures and unsatisfactory efficiency in suppressing gene expression have become the technical difficulties that hinder their utility when studying gene knockdown....

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Xin, Haoran, Lei, Mingxing, Zhang, Zhihui, Li, Jie, Zhang, Hao, Luo, Xinwei, Wang, Aoyun, Deng, Fang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120749/
https://ncbi.nlm.nih.gov/pubmed/30161025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.08.004
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