Suppression of IGF1R in Melanoma Cells by an Adenovirus-Mediated One-Step Knockdown System

Abnormal activation of the IGF1R signaling pathway accelerates melanoma development and metastases. RNAi systems with complex cloning procedures and unsatisfactory efficiency in suppressing gene expression have become the technical difficulties that hinder their utility when studying gene knockdown....

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Udgivet i:Mol Ther Nucleic Acids
Main Authors: Xin, Haoran, Lei, Mingxing, Zhang, Zhihui, Li, Jie, Zhang, Hao, Luo, Xinwei, Wang, Aoyun, Deng, Fang
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120749/
https://ncbi.nlm.nih.gov/pubmed/30161025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.08.004
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