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Durable complete responses in some recurrent high-grade glioma patients treated with Toca 511 + Toca FC

BACKGROUND: Vocimagene amiretrorepvec (Toca 511) is an investigational gamma-retroviral replicating vector encoding cytosine deaminase that, when used in combination with extended-release 5-fluorocytosine (Toca FC), results preclinically in local production of 5-fluorouracil, depletion of immune-sup...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Neuro Oncol
Main Authors: Cloughesy, Timothy F, Landolfi, Joseph, Vogelbaum, Michael A, Ostertag, Derek, Elder, James B, Bloomfield, Stephen, Carter, Bob, Chen, Clark C, Kalkanis, Steven N, Kesari, Santosh, Lai, Albert, Lee, Ian Y, Liau, Linda M, Mikkelsen, Tom, Nghiemphu, Phioanh, Piccioni, David, Accomando, William, Diago, Oscar R, Hogan, Daniel J, Gammon, Dawn, Kasahara, Noriyuki, Kheoh, Thian, Jolly, Douglas J, Gruber, Harry E, Das, Asha, Walbert, Tobias
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2018
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120351/
https://ncbi.nlm.nih.gov/pubmed/29762717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy075
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