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Durable complete responses in some recurrent high-grade glioma patients treated with Toca 511 + Toca FC
BACKGROUND: Vocimagene amiretrorepvec (Toca 511) is an investigational gamma-retroviral replicating vector encoding cytosine deaminase that, when used in combination with extended-release 5-fluorocytosine (Toca FC), results preclinically in local production of 5-fluorouracil, depletion of immune-sup...
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| Publicado en: | Neuro Oncol |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6120351/ https://ncbi.nlm.nih.gov/pubmed/29762717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy075 |
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