Construction of a set of novel and robust gene expression signatures predicting prostate cancer recurrence

We report here numerous novel genes and multiple new signatures which robustly predict prostate cancer (PC) recurrence. We extracted 696 differentially expressed genes relative to a reported PC signature from the TCGA dataset (n = 492) and built a 15‐gene signature (SigMuc1NW) using Elastic‐net with...

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Vydáno v:Mol Oncol
Hlavní autoři: Jiang, Yanzhi, Mei, Wenjuan, Gu, Yan, Lin, Xiaozeng, He, Lizhi, Zeng, Hui, Wei, Fengxiang, Wan, Xinhong, Yang, Huixiang, Major, Pierre, Tang, Damu
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120243/
https://ncbi.nlm.nih.gov/pubmed/30024105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12359
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