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Construction of a set of novel and robust gene expression signatures predicting prostate cancer recurrence

We report here numerous novel genes and multiple new signatures which robustly predict prostate cancer (PC) recurrence. We extracted 696 differentially expressed genes relative to a reported PC signature from the TCGA dataset (n = 492) and built a 15‐gene signature (SigMuc1NW) using Elastic‐net with...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Oncol
Hauptverfasser: Jiang, Yanzhi, Mei, Wenjuan, Gu, Yan, Lin, Xiaozeng, He, Lizhi, Zeng, Hui, Wei, Fengxiang, Wan, Xinhong, Yang, Huixiang, Major, Pierre, Tang, Damu
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120243/
https://ncbi.nlm.nih.gov/pubmed/30024105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12359
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