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Kinesin-2 heterodimerization alters entry into a processive run along the microtubule but not stepping within the run

Heterodimeric KIF3AC and KIF3AB, two members of the mammalian kinesin-2 family, generate force for microtubule plus end–directed cargo transport. However, the advantage of heterodimeric kinesins over homodimeric ones is not well-understood. We showed previously that microtubule association for entry...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Quinn, Sean M., Howsmon, Daniel P., Hahn, Juergen, Gilbert, Susan P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120217/
https://ncbi.nlm.nih.gov/pubmed/29991594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002767
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