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LRRC8 N termini influence pore properties and gating of volume-regulated anion channels (VRACs)
Volume-regulated anion channels (VRACs) are crucial for cell volume regulation and have various roles in physiology and pathology. VRACs were recently discovered to be formed by heteromers of leucine-rich repeat–containing 8 (LRRC8) proteins. However, the structural determinants of VRAC permeation a...
Gespeichert in:
| Veröffentlicht in: | J Biol Chem |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6120214/ https://ncbi.nlm.nih.gov/pubmed/29925591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002853 |
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