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Conserved motifs on the cytoplasmic face of the protein translocation channel are critical for the transition between resting and active conformations
The Sec61 complex is the primary cotranslational protein translocation channel in yeast (Saccharomyces cerevisiae). The structural transition between the closed inactive conformation of the Sec61 complex and its open and active conformation is thought to be promoted by binding of the ribosome nascen...
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| Publicado en: | J Biol Chem |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6120202/ https://ncbi.nlm.nih.gov/pubmed/29986881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004123 |
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