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Conserved motifs on the cytoplasmic face of the protein translocation channel are critical for the transition between resting and active conformations

The Sec61 complex is the primary cotranslational protein translocation channel in yeast (Saccharomyces cerevisiae). The structural transition between the closed inactive conformation of the Sec61 complex and its open and active conformation is thought to be promoted by binding of the ribosome nascen...

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Foilsithe in:J Biol Chem
Main Authors: Mandon, Elisabet C., Butova, Cameron, Lachapelle, Amber, Gilmore, Reid
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120202/
https://ncbi.nlm.nih.gov/pubmed/29986881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004123
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