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Cell surface expression of homomeric GABA(A) receptors depends on single residues in subunit transmembrane domains

Cell surface expression of type A GABA receptors (GABA(A)Rs) is a critical determinant of the efficacy of inhibitory neurotransmission. Pentameric GABA(A)Rs are assembled from a large pool of subunits according to precise co-assembly rules that limit the extent of receptor structural diversity. Thes...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Hannan, Saad, Smart, Trevor G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120189/
https://ncbi.nlm.nih.gov/pubmed/29986886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002792
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