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Mouse models in the era of large human tumour sequencing studies
Cancer is a complex disease in which cells progressively accumulate mutations disrupting their cellular processes. A fraction of these mutations drive tumourigenesis by affecting oncogenes or tumour suppressor genes, but many mutations are passengers with no clear contribution to tumour development....
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| Publicado no: | Open Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6119864/ https://ncbi.nlm.nih.gov/pubmed/30111589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.180080 |
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