Complementary middle-down and intact monoclonal antibody proteoform characterization by capillary zone electrophoresis – mass spectrometry

High-resolution capillary zone electrophoresis – mass spectrometry (CZE-MS) has been of increasing interest for the analysis of biopharmaceuticals. In this work, a combination of middle-down and intact CZE-MS analyses has been implemented for the characterization of a biotherapeutic monoclonal antib...

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Detalhes bibliográficos
Publicado no:Electrophoresis
Main Authors: Belov, Arseniy M., Zang, Li, Sebastiano, Roberto, Santos, Marcia R., Bush, David R., Karger, Barry L., Ivanov, Alexander R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6119659/
https://ncbi.nlm.nih.gov/pubmed/29749064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/elps.201800067
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