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Glycosaminoglycan Synthesis in the Nucleus Pulposus: Dysregulation and the Pathogenesis of Disc Disease

Few human tissues have functions as closely linked to the composition of their extracellular matrices as the intervertebral disc. In fact, the hallmark of intervertebral disc degeneration, commonly accompanying low back and neck pain, is the progressive loss of extracellular matrix molecules - speci...

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Detalhes bibliográficos
Publicado no:Matrix Biol
Main Authors: Silagi, Elizabeth S., Shapiro, Irving M., Risbud, Makarand V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6119535/
https://ncbi.nlm.nih.gov/pubmed/29501510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2018.02.025
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